What is Ovarian Rejuvenation therapy?

Ovarian Rejuvenation is a modern regenerative treatment designed to help women restore ovarian activity and improve egg quality using their own biological material — typically Platelet-Rich Plasma (PRP) or Exosomes.

Who is the therapy suitable for?

It’s recommended for women with low ovarian reserve, early menopause, diminished AMH levels, or those who haven’t responded well to previous IVF stimulation.

How does the procedure work?

The process involves taking a small sample of your own blood, isolating growth factors or exosomes, and gently injecting them into the ovaries under ultrasound guidance. These biologically active substances stimulate tissue regeneration and follicle activation.

Yes. Since the material comes from your own body, there’s no risk of rejection or allergy. The procedure is minimally invasive and performed under light anesthesia by experienced reproductive specialists.

How long does the procedure take?

The entire process takes around 30–40 minutes, including preparation and recovery. Most patients return to normal activities the same day.

What results can I expect?

Many patients experience improved ovarian function within 2–3 months. This may include increased AMH levels, the return of menstruation, or the ability to produce mature eggs for IVF. Results vary individually.

Can it help me get pregnant naturally?

In some cases, yes. Restored ovarian activity can lead to spontaneous ovulation and natural conception, but results depend on age and baseline ovarian function.

How soon can I start IVF after the procedure?

Typically within 6–8 weeks, once hormone levels and ultrasound indicators show ovarian response. Your IFG fertility specialist will guide the exact timeline.

What’s the difference between PRP and Exosome therapy?

PRP uses your own blood plasma with concentrated growth factors, while Exosome therapy delivers even smaller bioactive particles that enhance cell regeneration. Exosomes are often more potent for cellular repair.

Is Ovarian Rejuvenation painful?

The procedure is performed under anesthesia and is usually well tolerated. Mild discomfort or spotting may occur for a day or two afterward.

How many treatments are needed?

Usually one session is enough, but in some cases a follow-up may be advised after 6 months depending on ovarian response.

Are there any risks or side effects?

Side effects are minimal. Temporary pelvic discomfort or mild cramping may occur. As it’s autologous (your own material), infection or allergic reactions are extremely rare.

Can I combine Ovarian Rejuvenation with IVF or Egg Donation

Absolutely. It can be performed before IVF to improve egg quality or as preparation before using donor eggs — enhancing endometrial and ovarian receptivity.

Where can I do the procedure?

IFG offers Ovarian Rejuvenation programs through its partner clinics in Georgia, Slovakia, Albania, and Ukraine, ensuring full medical and logistic support.

Who performs the treatment?

The procedure is carried out by certified reproductive specialists under the supervision of Dr. Uliana Dorofeyeva and Dr. Birol Aydin, IFG’s leading experts in regenerative reproductive medicine.

Ovarian
Rejuvenation:

A New Hope for Your Journey.

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At IFG, we understand how difficult it can be to hear that your chances of having a biologically related child are over. But we believe that science and hope can offer a new path. Our Ovarian Rejuvenation Therapy is designed for women who are determined to improve the quality and quantity of their own eggs, even after facing multiple setbacks. With our expertise and care, there’s always a chance to pursue your dream of parenthood.

A Renewed Chance When Options Are Fading

Low ovarian reserve. Early menopause. Poor response to stimulation. These are heavy words, but they don’t have to define your journey. Ovarian Rejuvenation uses your body’s own healing cells and regenerative technologies to help reawaken egg development inside the ovaries, offering a natural boost in the right direction.

At IFG, we offer three distinct Ovarian Rejuvenation treatments, each designed to meet different needs and circumstances, giving you more than one path forward.

Microscope

Adinizer – Innovations in Regenerative Medicine

Adinizer uses ultra-sharp, CE- and FDA-certified blades to collect regenerative cells from your own fat tissue. These cells are then isolated in a sterile, closed system and reintroduced into your ovaries to support repair and hormone balance. It’s minimally invasive, highly efficient, and designed for a smoother recovery. To ensure the highest level of precision and safety, we bring in the expertise of a skilled plastic surgeon to perform the procedure.

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Woman

PRP + Exosomes – Transforming Ovarian Rejuvenation

This treatment combines PRP (platelet-rich plasma, derived from your own blood) with exosome technology to support ovarian repair. Exosomes are proteins that enhance cellular communication and are sourced from an FDA-approved stem cell bank. This powerful combination has shown potential to improve egg quantity, embryo quality, and IVF success rates, while reducing the number of cycles needed for results. You can expect to see improvements within approximately 3 menstrual cycles post-procedure.

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Treatment for Women Who Believe in Possibility

You might be a good candidate if:

You’ve been diagnosed with low AMH or poor ovarian response
You’ve entered early menopause or are approaching it
IVF hasn’t worked, or you’ve been told to consider donor eggs
You want to try one more time with your own eggs

We’ll take a close look at your hormone levels, cycle history, and goals to see if this could be the right next step for you.

What Makes This Journey with IFG So Different

We know this is more than a procedure; it’s a deeply personal path forward. That’s why we combine cutting-edge science with heartfelt, respectful, care.

No hormone-heavy protocols—just thoughtful, targeted treatment
Minimally invasive, outpatient procedures with minimal downtime
Science-based treatments performed by globally recognized fertility experts
Gentle, compassionate guidance from a team who truly listens

Discover the difference of a personalized fertility journey designed around you.

A Simple, Supportive Process—Centered Around You

We believe your experience should feel empowering and stress-free. That’s why our ovarian rejuvenation process is thoughtfully designed with clarity, care, and your personal journey in mind.

1
Connection & Education
Begin with a friendly conversation with our Client Service Team. We’ll listen to your story, answer your questions, and guide you through the services that may best support your goals—all with clear pricing and no surprises. We're also happy to share our impressive statistical outcomes to help you feel informed and confident from the very start.
2
Consultation & Personalized Evaluation
Next, you’ll meet with our physicians and dedicated coordinators for a personalized consultation. Together, you’ll review your cycle history, AMH levels, and complete hormonal profile. This is your opportunity to ask any medical questions directly to our clinical team and explore the rejuvenation approach that best aligns with your body, needs, and goals.
3
Rejuvenation Procedure
When it's time for your procedure, we’ll carefully collect the material needed for your personalized therapy, whether it’s your own blood, fat tissue, or thoroughly screened donor cells. Your treatment is then prepared and administered under precise ultrasound guidance to ensure safety and effectiveness. The procedure is outpatient and, if needed, can be paired with an egg retrieval to make the most of your time under anesthesia, maximizing both comfort and efficiency.
4
Monitoring Your Response
After your procedure, you’ll be able to return to your normal routine within just a day or two. From there, our team will gently guide you through the next steps, keeping a close eye on hormonal shifts and early signs of ovarian activity. We’ll be by your side, helping you understand how your body is responding and making thoughtful adjustments to support the best possible outcome.
5
Planning What Comes Next
As your progress becomes clear, we’ll help you explore the next phase of your journey—whether that means preparing for IVF or trying to conceive naturally. If a second round of treatment would be helpful, rest assured that the procedure can be safely repeated. No matter your path, you won’t be walking it alone—our team will be with you, offering guidance, encouragement, and care at every step.

Ongoing Support Every Step of the Way

After your procedure, we’re right there with you, providing continuous support as you progress. Whether your response is quick or gradual, our team remains by your side, closely monitoring hormone levels and ovarian activity to keep you informed and confident. If necessary, we’ll adjust your care plan or repeat the procedure to maximize your chances of success. You’re never alone in this journey.

How quickly might I see changes?
Most women notice early hormone shifts or a few new follicles within three to six menstrual cycles, depending on the therapy chosen.
Will the procedure be painful?
Discomfort is usually mild—similar to period cramps—for a day or two. Over the-counter pain relief and light activity are enough for most patients.
Can ovarian rejuvenation be combined with IVF?
Yes. Many women rejuvenate first to boost egg quality, then start IVF once new follicles are visible on ultrasound.
How many treatments will I need?
One session is standard. A booster round is an option after six months if labs improve yet follicle numbers remain low.
What risks should I know about?
Minor soreness, light spotting, or temporary bloating can occur. Infection or rejection is very rare thanks to sterile technique and rigorous cell screening.
Does this replace donor eggs?
Rejuvenation offers a final chance with your own eggs. If egg quality still falls short, donor eggs remain available.
What will it cost?
Most women notice early hormone shifts or a few new follicles within three to six menstrual cycles, depending on the therapy chosen.

Ready to Try ? We’re Here

Let us help you fulfill your dream of holding your child in your arms.

With IFG by your side, hope transforms into action. Let us be the bridge that leads you to the family you have always imagined.

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FAQ

What is Ovarian Rejuvenation therapy?
Who is the therapy suitable for?
How does the procedure work?
Is it safe?
How long does the procedure take?
What results can I expect?
Can it help me get pregnant naturally?
How soon can I start IVF after the procedure?
What’s the difference between PRP and Exosome therapy?
Is Ovarian Rejuvenation painful?
How many treatments are needed?
Are there any risks or side effects?
Can I combine Ovarian Rejuvenation with IVF or Egg Donation
Where can I do the procedure?
Who performs the treatment?

Ovarian Rejuvenation Therapy with Regenerative Fertility Support

Ovarian regeneration therapy and ovarian function restoration are becoming increasingly relevant options for patients dealing with low ovarian reserve, poor IVF response, early ovarian aging, or those who want to explore the possibility of using their own eggs before considering donor options. International Fertility Group (IFG) supports patients in understanding whether these approaches are suitable for their situation, coordinating access to regenerative fertility treatments through qualified reproductive specialists.

Guidance for Patients Exploring Ovarian Function Restoration

Determining whether ovarian function restoration is a relevant step begins with a thorough review of each patient's hormone levels, AMH and FSH results, ovarian reserve, IVF history, age, and overall fertility goals. IFG works with patients to make sense of this picture before any treatment decisions are made, connecting them with reproductive specialists who can assess the case and explain what regenerative options may realistically offer. The focus is on building an informed, honest understanding of the situation rather than moving forward without a clear medical basis.

Regenerative Options Beyond Standard Fertility Treatment

Ovarian rejuvenation sits within a growing field of regenerative reproductive medicine that offers alternatives for patients who have not responded well to standard fertility treatment. IFG coordinates access to different approaches within this field, including PRP with exosomes and Adinizer ovarian therapy, as well as other methods of ovarian reserve restoration therapy. Each approach is evaluated based on the patient's individual profile, with non–surgical ovarian rejuvenation methods considered where medically appropriate. The choice of method is always guided by a proper clinical assessment, not a one–size–fits–all recommendation.

Understanding Treatment Options, Costs and Expectations

The cost and structure of ovarian rejuvenation treatment depends on several factors: the patient's ovarian reserve and hormonal indicators, IVF history, age, the chosen technology, and the country where treatment takes place. IFG does not offer guaranteed outcomes, as results vary based on individual medical circumstances. What patients receive is a transparent consultation process, an honest medical evaluation, and a realistic picture of what their treatment plan would involve before making any decisions.

Ovarian Rejuvenation: